By Ping-Chung Leung; Harry Hong Sang Fong; Charlie Changli Xue
Текущий обзор китайской медицины: контроль качества трав и травяных материалов the second one quantity of this e-book sequence at the glossy perform of chinese language medication maintains with the focal point on evidence-based TCM study. it really is considering distinctive information regarding the simplest assets of natural offer and its qc required for examine and drug improvement reasons. natural caliber has continually been an enormous drawback for TCM researchers since it is hard to grasp that's of the highest quality. another well known subject matters also are entertained. Во втором томе этой серии книг продолжается разговор о современной практике китайской медицины с акцентом на фактические данные её исследований. Он ориентирован на подробную информацию о лучших источниках поставок лекарственных растений и контроле их качества, необходимых для проведения исследований и приготовления лекарств. Качество сырья всегда было серьезной проблемой для исследователей TКM. Первый том этой же серии, «Chinese Medicin. glossy Practice», содержит главы, также посвященные лекарствам китайской травяной медицины.
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Additional resources for Current Review of Chinese Medicine: Quality Control of Herbs And Herbal Material
Fong et al. identification of the eluting "peak". A third commonly used detection technique is evaporative light scattering detection (ELSD), as a vast majority of all plant secondary metabolites are detectable whether or not they contain a spectroscopically active chromophore. In the case of the two herbs under study for safety and efficacy, the bioactive marker compounds in T. pratense were identified as the isoflavones formononetin (1), daidzein (2), biochanin A (3) and genistein (4). These compounds possess conjugated aromatic chromophores, which are amenable to HPLC-UV detection, and were so analysed (Booth et al, 2006).
In a limited pharmacokinetic study on T. pratense, we encountered no bioavailability problems as demonstrated by our being able to quantitatively determine the level of the bioactive markers formononetin (1), daidzein (2), biochanin A (3) and genistein (4) in the blood (Fig. , 2004). In the case of C. racemosa, two classes of compounds were found to be active in the 5HT7 in vitro bioassay. /-26-deoxyactein (7) showed 100 m/z 500-900 c5 E o o
Procedures for the quality control analysis of active marker chemical compounds can be accomplished by colourimetric, spectroscopic and/or chromatographic methods. Colourimetric and direct spectroscopic methods are older analytical procedures quantifying the absorption of structurally related compounds at a specific wavelength of light, and expressed as concentration of a reference standard (marker). Since other plant constituents possessing the same absorbance are included in the measurement, a higher concentration is usually ascribed to the test material.